Alfresa Holdings Corporation, operating through its subsidiaries, is a diversified entity involved in the production, distribution, marketing, and international trade of pharmaceuticals, diagnostic reagents, and medical devices. Its operations span Japan and global markets. The company's core activities include the ethical pharmaceuticals wholesale business, which supplies diagnostic reagents and medical equipment to a range of healthcare providers such as hospitals, clinics, and dispensing pharmacies. Additionally, it runs a self-medication products wholesale segment, distributing over-the-counter (OTC) drugs, health foods, nutritional supplements, and other wellness products to retail pharmacies and drugstores. Beyond distribution, Alfresa also manufactures and markets active pharmaceutical ingredients (APIs), various pharmaceuticals, diagnostic substances, and medical devices, and provides contract manufacturing services for pharmaceuticals. Furthermore, its medical-related division encompasses the operation of dispensing pharmacies and other associated healthcare activities. Alfresa Holdings Corporation was established in 2003 and is headquartered in Tokyo, Japan.